Comparison of Serum Soluble Corin Levels among Stroke Subtypes

Results: Serum soluble corin level was significantly higher in ischemic stroke patients than hemorrhagic stroke patients in men (log-corin, mean±SD:7.53±0.34 vs. 7.42±0.28; P =0.013) and women (log-corin, mean±SD:7.22±0.27 vs. 7.12±0.31; P = 0.044). Then we studied serum soluble corin in subtypes of ischemic stroke. Unadjusted analysis failed to show a significant difference in logtransformed serum soluble corin among different ischemic stroke subtypes in both men and women. However, after adjustment for the covariables, the mean level of log-transformed serum soluble corin was significantly increased in embolic stroke patients compared with other subtypes in men (P <0.05). In women, embolic stroke patients also had the highest mean level of log-transformed serum soluble corin but with no significant difference. After excluding patients with a history of coronary heart disease, the mean level of serum soluble corin was still the highest in embolic stroke patients among men and women however with no significance.